Why Is An Ancient Disease Still Killing Millions?

Stephan Schwander (Director, Center for Global Public Health; Rutgers School of Public Health)
Chrispin Kambili (Global Medical Affairs Leader, Global Public Health, Johnson & Johnson)

This seminar explores the global health priorities and disease burden, including HIV/AIDS, malaria and tuberculosis, diarrheal diseases and respiratory infections in children. We will look at global disparities, and the influence of poverty and socioeconomic status on the communicable diseases. Additionally, environmental factors, climate change and urbanization will be explored as a source of new challenges and opportunities for changes in the global public’s health. As a case study, we will look specifically at tuberculosis (TB), an ancient disease and the number one infectious killer globally. Despite scientific and social advances, a high burden of TB persists worldwide. We will review the underlying infection with Mycobacterium tuberculosis (M.tb), the responses of the bodies’ defense system to the infection, diagnosis, treatment and prevention of TB, drug resistance, the lack of drug options and difficulties to access drugs and the efficiency of health systems in low and middle income countries. We will discuss the social determinants underlying the M.tb infection and TB the need for new drugs, including bedaquiline, the first new tuberculosis drug developed in the past 40 years. To deepen our understanding, we will consider the challenges of developing new medications, the ethics of testing new drugs, and the important contributions needed to control the global tuberculosis pandemic.

Course Number: 
01:090:101 section 96 index 12424