Making Mutants: Understanding the Control of Gene Expression
The control of gene expression is one of the fundamental processes in all organisms, and unregulated gene expression is often the cause for cancer and other diseases. Understanding how gene expression is regulated will help researchers develop mechanisms to combat disease. This course will discuss current research in the yeast Saccharomyces cerevisiae that is being used to understand the process of gene regulation in eukaryotes. Students will get first-hand laboratory research experience by performing experiments to isolate and analyze mutants in a protein that regulates transcription in yeast and is involved in higher organisms.