Physiology is a classic natural science. It is recognized by the Nobel Committee, in part, through the annual Nobel Prize in Physiology or Medicine. For example, Selman Waksman was awarded the Nobel Prize in Physiology or Medicine in 1952 for his discovery of streptomycin, the first antibiotic (a term Waksman coined) effective against tuberculosis. Waksman is the only Rutgers University faculty member (thus far) to have received this honor. Physiology is also an experimental science. Prof. Merrill’s interests have focused on the cardiovascular system and its regulation in health and disease. For example, experimentation in our laboratory at Rutgers was the first to demonstrate previously-unknown, but significant, cardiovascular effects of the popular analgesic, acetaminophen. In experimental animals, acetaminophen is both cardioprotective and cerebroprotective against the damaging consequences of ischemia/reperfusion injury, myocardial infarction, and simulated stroke. In this course, students will be exposed to a combination of lectures on classic cardiovascular physiology, discussion of related topics of interest to medicine, and innocuous experiments designed to improve one’s appreciation for the human cardiovascular system and how to care for it.